During a pre-bedtime scroll through TikTok I was coming across multiple videos of people explaining that when their nipples are touched, either by themselves or others, they feel a great sense of sadness, loss, and other varying negative emotions. One TikTok user compared the sensation to “guilt and almost something like homesickness.” If you’ve read my other nipple article, you’ll know I’m a big fan of nipple play. Whilst I was aware that some people simply find no joy in nipple stimulation, I was not aware that for others, the sensation of touching their own nipples brought such negative feelings, nor was I aware that Sad Nipple Syndrome existed at all. Hence this article aims to uncover the reason and science behind it, to enlighten both me and anyone else curious to expand their nipple knowledge.
Whilst there have been articles on the connection between sadness and nipple stimulation in the past, it has only been in the context of lactation and breastfeeding. Dysphoric Milk Ejection Reflex (D-MER) is defined as an “abrupt emotional drop that occurs in some women just before milk release and continues for not more than a few minutes.” For D-MER, direct nipple stimulation was not needed for the onset of negative emotions, instead, it could be triggered by anything that caused a milk release. D-MER symptoms further seem to form a spectrum of distinct and different emotions—depression, anxiety, and anger—the intensity of this varies from each person. Its lack of research and discourse has meant that it’s still greatly misunderstood, with the primary belief being that it is influenced (within minutes or hours) by circumstances that influence dopamine levels.


















